You kinda left out information that is necessary in order to tune the system to your sim. Your monitors operating resolution as well as your cpu is needed in order to give the absolute best advice.
But anyway
Install the driver. Do not make any changes to the settings in terms of image processing within the radeon software (standard profile). Leave it stock. (make sure vsync /freesync is off within the radeon software)
Run the sim … Within the sim general display settings run the sim at ultra settings at your monitors default resolution. Turn on Vsync within the sim and set it to 30 (The sim will still go over 30 fps dont worry)
Start a flight and from within the cockpit (and only the cockpit press ALT R) it will bring up the radeon software. Go to performance and tuning and look for the little switch that turns on the monitoring overlay that will show you your gpu usage fps wattage and temps in the upper right corner of your monitor.
After you have that up and running your next step is to balance the card to the processor.
To do that you will need to fly in a decently resource demanding area (Not london thats bugged atm) … Preferably NYC or Tokyo and observe the framerate and gpu usage. If your getting a bunch of stutters and the gpu is showing low usage then go back to general display settings in the sim and up the render scaling by 10… till most of the stutters are gone and the gpu is running at 100%. IF the gpu is already at 100% and you feel that the performance is not up to par in terms of framerates you have two options. Either back off some of the ultra settings within the sim or back off the render scaling by 10.
The aim is to make sure that the GPU is running at 100% or pretty close to it in most if not all cases.
Caution !!
please be aware that presently there is a bug that randomly causes GPU’s to drop in their usage since the UK update so please be on the lookout for this during testing and be able to tell the difference between your gpu not being 100% from being properly optimized and and not being 100% because the bug hit at some random point during your flight.
Thats the basics.
My current system
AMD Ryzen 5900x / 32gb ram/ AMD Powercolor 6800xt
Advanced
Once you have the sim running smoothly then you can go into the performance section of the radeon software and experiment with the various tuning and overclocking options for better performance or more gpu headroom if you want more performance from the card (But this may be unecessary unless your running 4k/ultra and maxed out card and the frames are still low)