Warning: long post ahead!
I used to have a 180-degree curved screen setup. It was just small enough to allow me to get away with 2 projectors. This was with P3D as the main sim, and one PC used as an image generator with another as the host sim system.
I didn’t regret my choice, but there were drawbacks. First, it was expensive. The screen and projector gantry were self-made, and not hugely expensive to make, but then I needed two short-throw projectors and when one developed an irreparable fault several years later, I had to buy two replacements because that model was no longer made and you absolutely need matched pairs of projectors. That hurt, let me tell you! Then the extra software I needed was very expensive because it’s so specialist. It’s cheaper than it used to be but you’re still going to be spending thousands.
There are other practical problems. Getting the image corrected for the shape of the screen is painful. You can’t really eyeball it satisfactorily, you need tools to help you. Believe me, I tried, but with a screen that large that wraps around you, any imperfection / deviation will drive you mad. I also had some issues with focus at the extremes of the screen; projectors are made to focus at a flat plane, and depending on the radius of your screen, you might find you have to compromise on some softness of focus in some areas of the image.
There’s also the issue of squashing / expanding the image, which is done by the warping software. After warping, the pixels in the warped image no longer correspond 1:1 to pixels on the projector image, so you get areas where effectively a single image pixel is represented by less than a single ‘real’ pixel, and vice versa. This gives some area of the image less sharpness, and can manifest in some odd artifacts that you can’t stop noticing once you see them. It’s less of an issue with a 3 projector system than a 2.
My projectors would drift out of precise alignment over time. A simple matter of the mounts not being 100% rigid, me having a train line not far from my house causing vibrations, and heating/cooling cycles in the projectors causing the lens assembly to shift minutely. So every few weeks I’d have to do a re-alignment exercise, or else the part of the image when the two projectors overlap would become blurred. Speaking of which, you’ll get a bright grey stripe where the projectors overlap when the screen should be black. This is the ‘black offset’ problem and while there are ways to solve it, none are perfect and doing it ‘properly’ is… you guessed it! Expensive. I did come up with a DIY solution which sort-of worked, but never perfectly.
The projectors kick out a major amount of heat. Add the multiple PCs to that, and my room could easily get up past 40C after a couple of hours. In summertime that could be enough to overheat the PCs, so I had to buy aircon for cooling and still the sim room would become a sauna. There are ways to tackle this but they were beyond my engineering skills.
Finally, the other big issue is perspective correction. You can map your display to the curve of the screen, that’s fine, but then a straight line (like a runway) seen perpendicular ahead of you will appear curved around the screen. So you need to correct this. In P3D this would be done by creating a ViewGroup with individual view frustums for each view (2 or 3, one per projector) calculated so that after the image is warped the views align in precisely the right way to cancel out the curve and make straight lines appear straight. It’s magical when you see it the first time, but it’s just maths. However, the software to make the maths go is complex and - again - expensive.
With MSFS, you don’t have the ability to define view frustums or move the origin, which makes the above much closer to impossible. Fly-Elise NG (who make the warping software I used to use) does now have an experimental system that can sort-of do it using the experimental MSFS multi-view capability (or a multi-channel system) but my understanding is that your setup has to fit very specific requirements for this to even work. Until and unless MSFS gets individually-definable view frustums and cameras per-view, doing what you can do in P3D and X-Plane will remain impossible. TBH I don’t think we’ll ever get it, I don’t think it’ll ever be high enough up the list for Asobo to spend time on it.
So, given all the above, why didn’t I regret my decision? Well, you have to see and sit inside a wraparound screen running a sim with full perspective correction to believe it. It’s just amazing. LCD screens have a better image, but they are flat - which introduces distortion - and have poor viewing angles, and bezels.
Ultimately, though, I decided to demolish mine and build something new. Originally intended to be a better projector system, but I’ve more or less decided to go with big TVs, which will work better with MSFS. But life got in the way and I haven’t even started it yet, so my current setup has only a single large TV for a display, and you have no idea how much I miss the situational awareness of being able to look left or right and just see straight out the window without any TrackIR nonsense.
If you have deep pockets and don’t tend to regret spending big chunks of cash for the sake of experience, I’d say go for it. You’ll definitely have fun 
At the risk of a tiny bit of self-promotion, there are some videos shot in my old cockpit, and a bunch of video on the display tech and its setup, on my YouTube channel.
