Can't switch to VR mode anymore after reinstall

I just reinstalled my Windows 10 and MSFS. Unfortunately I can’t switch to VR Mode within the sim anymore. If I hit the Button nothing happens. My headset works fine and is properly recognized by windows and WMR also works without issues. I just can’t to switch to VR mode in the game.
I remember having this problem the very first time when bought my Reverb G2 and I somewhere read on how to solve this issue. Unfortunately I can’t recall where I read that.

Appreciate your help.

Check your key bindings in the sim for switching to VR. Is it set to use CTRL-TAB?

When you run Mixed Reality Portal, do you see that?

Alternatively, can you download OpenXR Tools for Windows Mixed Reality from the Windows Store and try that:

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That was it. Thanks a lot for your help!!

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