Well I did it! I’m a brave warrior who challenges de status quo. 
First flight was successful. Now the question is if the pagefile was the solution or if it was just luck (happened in the past). I hope to find some more time in the course of the week to answer this question. I’ll report when I know more.
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I was able to do some short flights over the course of the week and so far no crashes. So looks good. Unfortunately I can’t tell if the pagefile solved the problem or the reinstall of all gamefiles.
One thing that got my attention is a decrease in performance. While FS was running smooth before, now there are some stutters from time to time.
I just installed Sim Update IV and CTDs are back…
Same as in the past: VCRUNTIME140.dll and 0xc0000005.
Before installing Sim Update IV, I had no crashes after setting the pagefile as told.