Have you tried
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looking at these settings to see they are not accidentally dis/enabled-
Options - Assistance - Aircraft Systems - Unlimited Fuel
Options - Assistance - Aircraft Systems - Failure & Damage - Engine Stress Damage
Options - Assistance - Aircraft Systems - Failure & Damage - Icing Effects -
Auto starting the engines again (keyboard CTRL-E)
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Tried passing control to the AI pilot (not the auto pilot) to see if they can find a way of turning everything back on again even if just for a minute or two.
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Checking your mixture hasn’t been changed even accidentally
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Research on here shows that there was a bug relating to mixture on prop planes in 2020. Don’t know if was ever fixed. It may be worth researching further -
I’ve not seen this happen before, but I don’t spend a lot of time in the smaller prop planes other than the BN-2.