I have noticed problems similar to this have been raised a few times in the past affecting the Thrustmaster TCA throttle but now I am getting a very similar problem with the Honeycomb Bravo Throttle
When I have Bravo Throttle connected and press ESC (PAUSE) and it displays the 3 general options menu, when I then press ESC again to resume flight I find that the throttles have been moved to mid position the flaps have been extended and the spoilers fully deployed.
Even after starting a blank new profile as soon as I assign a throttle axis the problem is back. Anyone else experiencing this with Bravo Throttle, looking back through the forum it looks like its affecting different controllers at different times.
I was beginning to think I had a duff Bravo Throttle but having checked the forum I think MSFS 2020 is to blame.