I have noticed problems similar to this have been raised a few times in the past affecting the Thrustmaster TCA throttle but now I am getting a very similar problem with the Honeycomb Bravo Throttle
When I have Bravo Throttle connected and press ESC (PAUSE) and it displays the 3 general options menu, when I then press ESC again to resume flight I find that the throttles have been moved to mid position the flaps have been extended and the spoilers fully deployed.
Even after starting a blank new profile as soon as I assign a throttle axis the problem is back. Anyone else experiencing this with Bravo Throttle, looking back through the forum it looks like its affecting different controllers at different times.
I was beginning to think I had a duff Bravo Throttle but having checked the forum I think MSFS 2020 is to blame.
Press the ESC key to bring up the menu, and all AXIS will move to the middle position. Then move the throttle to return.
Also, when I look at the Bravo preset at that time, it is always set to Default. However, it is only the name, not the actual selection. If I re-select some of the presets, it returns to normal.