Initial options (Accessibility, Graphics, etc.) requested every time MSFS is started

Do you have any add-ons in your Community folder? If yes, please remove and retest before posting.
I have tried to start MSFS without any addons or external connections (i.e. Navigraph Simlink et al)
Are you using Developer Mode or made changes in it?
Dev mode not enabled or altered
Brief description of the issue:
When I start MSFS the Accesibility Options open, then Graphic settings etc., as if it was the first time.
Provide Screenshot(s)/video(s) of the issue encountered:
N/A
Detail steps to reproduce the issue encountered:
I have opened MSFS with no addons and as an administrator, saved options, closed MSFS, and reopened (again, in adminstrative mode), and the same options occur during startup.
PC specs for those who want to assist (if not entered in your profile)
Windows 10 (recently updated) Not sure what was updated
Did you submit this to Zendesk? If so, what is your ticket #?
No

UI broken and reset user settings - Bugs & Issues / Performance, Graphics & CTDs - Microsoft Flight Simulator Forums