So Saitek panels seem to have an issue with enhanced USB saver feature of Windows 10. Go to this archived page (original since has been removed) to download the utility. Right click and run as admin and it will find any SAITEK devices and disable the reigstry for usb power saving for you. If you ever move the devices to another USB port you will have to rerun it again. Fixes especially issues with the Saitek Instrument panels not working but applies to any SAITEK equipment.