From driver version 572.16 up to 577.00, with the NVIDIA app installed, MSFS 2020 will crash to desktop during loading if running in DX11.
Starting from driver version 580.88 CTD during loading happens even without the NVIDIA app.
So, if someone wants to play MSFS 2020 with DX11 and driver versions 572.16 to 577.00, they should avoid installing the NVIDIA application. If they want to use the latest drivers, MSFS 2020 has to be set to DX12 instead of DX11 until a fix is released.