Please note that on certain hardware configurations, Process Lasso can have an impact on performance, specifically causing stuttering in MSFS and other games. For this reason, I recommend using it with caution.
Source https://forums.flightsimulator.com/t/process-lasso-for-msfs24/723604/4?u=tenpatrol
When I was still using Intel (I spent 30 years with Intel CPUs), I always had the E-Cores disabled in the BIOS because they negatively affected game performance. I recommend you do the same - disable the E-Cores in your BIOS settings.
Also disable virtualization in BIOS settings.
As for Process Lasso, it’s unnecessary in this case. These days, it’s mainly useful for Ryzen CPUs that have multiple CCDs.
edit
If you’re troubleshooting performance in MSFS, you should test the game completely clean - with no add-ons and no background programs running. I strongly recommend uninstalling any third-party add-ons and background tools while testing.
Also, connect only a wired mouse, keyboard and joystick to the PC. Disconnect all other USB devices to avoid unnecessary interference or system overhead.