I am new to FS, using a TM 16000 Stick and Throttle.
When I did some lading scenarios this issue occured first time (not every time!), now even in the flight class I was distrubed heavily:
Suddenly and without changing anything in the setup of my plane, the pitch goes crazy (sometimes nose hard up, one time even hard down) and the throttle (which can be fixed quite simply having an hardware throttle in hand) pushes to the max.
Occured in mutliple plane types by every approx. third flight.
For some strange reason I had the same issue in the first flights after purchase and fresh install of MSFS. Mainly during takeoff, but could happen anytime during flight. I really had to work the trim. But somehow it seems to have corrected itself. I don’t have the same problem and I’ve not done anything in the settings, that I’m aware of, that should fix it.