Pilot0083 is my go to for anything xbox related. Has some great tutorials particularly in using the garmin
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easyjetsimpilot
british avgeek
av angel
into the blue simulations
pilot studd
filbertflies
swiss 001 lol
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Clumsy Geek, excellent channel!!
These are my fav 
A B738 Captain with excellent content, lots of flight deck footage.
The one and only Mike Patey, his skills and work ethic are next level
777 Captain who analyzes incidents
He is a 747 freighter pilot who does reaction vids, vlogs and answers questions
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easyjetsimpilot brilliant
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I am learning German. JayDee is great, but he speaks too fast!
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Overkill Simulation is my first goto for all things MSFS2020
Easyjetsimpilot
Much appreciated! Thanks
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320 sim pilot -A320 pilot
Cgaviator -Hawk pilot
Corporate pilot dad - business jet pilot
Loads of excellent real world insight from these guys!
On the technical/hardware side I like Simhanger.
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Not so much MSFS2020, but for aviation in general: Mentour Pilot, fellow northener (love his clearly swedish accent), excellent visualized explanations of accidents and lots of technical stuff related to airliners
Someone mentioned 74Gear, that too for more easy going entertaining clips.
For MSFS2020 I have noticed going back again and again to
I like his honest style, easy to listen to.
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The only ones I can frequently tolerate are 320 Sim Pilot (he’s by far the best), British AV Geek, Obsidian Ant and EasyJet Sim Pilot.
Too many others have no clue what they’re actually talking about or are just 3rd party mod reviewers which I don’t find educational or entertaining.
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British AVgeek
P Gatcomb
Pilot Studd
Drawyah
FlibertFlies
If you want to check out real pilots and what info they have to share you can also check out
74 Gear
Captain Joe
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Ah someone is watching Mentourpilot. That´s a good channel! But he stopped filming all the technical details about the 737 and is currently making videos and discussions how aviation crashes or almost-accidents happened.
And his dogs seem to have disappeared. In every video I wonder where these two super-cute little fluffy dogs are hiding because they seem to have disappeared a year or 1,5 years ago.
Maybe he decided that these cute dogs don´t fit anymore to the dark gothic death-related theme his new videos now have, and that´s why they are not sitting with him on the couch anymore.
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In Spanish, a very good one with lots of videos of all kinds is GearUp
On Twitch only - not on you tube
- The Flying Fabio -
he is getting a good reputation with developers for passionate in depth looks at products, which often includes fly alongs with the developer in preview builds to discuss such as recent excellent in depth previews of the Big Radials Goose and SWS Kodiak.
These are streams and are lengthy - but I really enjoy most all the informative content he delivers while catching up with him on the VODs, these cover a wide range of aspects of aviation, products and the sim often mixing elements to deliver a better overall view of application and use.
Overall I find his content to be excellent, informative, in depth and thoroughly entertaining. I have awarded him my Prime subscription.
Youtube - Clumsy Geek and AV-Angel are regularly viewed and are also excellent viewing in there own unique styles.
Many good ones mentioned. I would also recommend Flightdeck2sim. He switches between MSFS and XPlane but enjoys flying both of them. Chilled and fun streams with lots of information and also do group flights. Real world 737 pilot. 
jeremy perez (very in depth and overall really pleasant) is my go to guy right now; also he always get back answering comment questions and playing on xbox which I can relate more in terms of setup and general workarounds. highly recommended
i usually watch also 320 sim pilot, kip on the ground (superb nxi tutorials), Filbert flies (he put a couple of in depth tutorials that were immensely valuable) and pilot 0083 (which is putting a lot of effort in showcasing new marketplace products so you can get an idea on what to expect)