Have you seen this thread on Zen 4 CPUs?
https://forums.flightsimulator.com/t/planning-on-buying-7800x3d-for-msfs-consider-the-7900x3d/585122
Agree with @BegottenPoet228, TLOD of 400 will stress your CPU for the aircraft and scenery you intend to use. TLOD of 150-200 is plenty for a good balance between visuals and performance when airliner flying.
TLOD of 400 is great for slow GA flying in the ‘backcountry’/middle of nowhere.
Personally, I think you should go for the GPU that has the most VRAM that you can afford. Developers don’t seem to care that their 4K (or even 8K) texture file sizes are swamping GPUs with < 12 GB VRAM. The combination of 8K textures on your payware airliner, 4K on FSLTL AI traffic aircraft and 4K on a payware airport scenery, suddenly makes for a worrying situation when using DX12.
Monitor resolution plays a key part in what GPU to buy. If you are serious about 2 monitors, you need to recognise that means the GPU is having to push a lot of pixels, something only the very top GPUs on the market can achieve.
One final point, the 980 Pro drive had a firmware issue. Just check the manufacture date to see if you may have a problem. However, it is fixable. Watch this video:
https://www.youtube.com/watch?v=DoAFzdz0h5M
Keep us updated!