The AI Pilot is supposed to be able to do this. My experience is VERY mixed. Generally (not always!) pushback/taxi/take off are OK and it usually follows the flight plan. Descent and landing are where things generally become unstuck.
To try it, set up a flight plan, load in the plane, then turn on AI Copilot from the (I think) assistance icon from the top menu bar…and pray!
If you want some laughs, worth flickign through this thread from August last year:
Charlie was bad enough then. I think he’s worse now because I suspect his coding has not been updated along with the sim updates and so all the changes to aircraft, avionics, flight model etc have not been built into his “thinking”…