I even had a CTD when my PC was turned off !!! 
This is why I always set up my SID directly to my flight plan on the world map. So the ATC will assign me the right runway.
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Hi all! Closing this topic due to duplicates that keep popping up. Please re-cast your votes on this topic:
https://forums.flightsimulator.com/t/ai-traffic-causing-ctd-when-clicking-fly/378694