you not get the safe-mode question and there is no new message in event log ?? Did you mean a Crash to Desk, or a application freeze ? In case of CTD it should be both things “exist”.
But you can force the Safe-Mode with place a file called running.lock to Roaming folder:
https://forums.flightsimulator.com/t/warning-notice-screen-on-start-up-remains/493942/4?u=michamma
EDIT: ah… you not own the Steam version… may the folder is different… I guess somewhere here:
…AppData\Local\Packages\Microsoft.FlightSimulator_8wekyb3d8bbwe\LocalState\running.lock