Msfs 2020 not running correctly (warning a running process may be interfering)

[Hester40MT]

Hi @CHKZIPILOT,
Are you running Process Lasso while running MSFS? There is a known issue with lasso that conflicts with MSFS:

KNOWN ISSUES (Last update: Sep. 17th, 2021) – Microsoft Flight Simulator Support (zendesk.com)

Also a small topic here:
Process Lasso - Bugs & Issues / CTDs - Microsoft Flight Simulator Forums