So I did a test flight with the S300 and the Thrustmaster TCA Sidestick. No problem at all. I even tried to use the twist axis for tail rotor control, which is of course not ideal, but possible.
Really the only “problem” with the S300 is that you need to adjust to the specific control delays of this helicopter. But that’s a core element of learning to fly any helicopter.
I cannot test the S300 on an XBox, as I don’t own one. But I cannot see any control issues on PC.
Now off to watching @FlightsWJoel 's new video on the S300 