NVidia's GEForce Experience degrades graphics performance

I had the same issue with older versions of ReShade, but the current Version 5.3.0 works just fine, even with DX12 on SU10 Beta.

This final light preset is all you need: FinalLight Reshade preset : Realistic colors and tone fixes for Microsoft Flight Simulator | MSFS

You need to pay attention during the shader install, as it relies on adding these shaders: GitHub - Fubaxiusz/fubax-shaders: A collection of post-processing shaders written for ReShade that I contribute to.

It’s a subtle removal of the greenish MSFS screen tint, but noticeable, and better. It’s all you need.
Note you do need to add a Lut texture it relies on to the reshade/textures directory.
You don’t want to overload on the post-processing as they also can add latency. Keep it simple.