Persistent Flight Simulator Crashes to Desktop

Did you try the fixes mentioned in the other thread you posted in?
https://forums.flightsimulator.com/t/msfs-2020-wont-finish-loading-with-openxr-toolkit-active/649731/16

and this recent post
https://forums.flightsimulator.com/t/fyi-oculus-software-causing-the-sim-to-crash/650460