Here’s an older thread that I started on this issue which includes some additional investigation:
I’ve never flown the SR22 despite owning the Premium Deluxe version prior to this sim update. Was the trim wheel working correctly before? If the inversion is a new phenomenon, then maybe that will make the cause easier to identify and correct.
I also really like the V1 trim wheel but between the axis reversals and sudden nose down behavior since SU11, it’s also been terribly aggravating. 