Why do some have CTDs and Others do not?

Agreed. Here’s what I posted on YACT (yet another CTD thread - Ctd hell! - #2 by trgz):

I have a PC that is littered with SDKs of various languages (C#, VB, Perl, Python, SQLLite, Unreal, yada yada); a couple versions of MS Office (2010, 2013); three versions of Visual Studio; around 150 installed games (>100 on Steam alone); dozens upon dozens of apps from many companies (iTunes, Google Earth, Photoshop, Garmin, FiiO, Comodo, AVG, Splashtop, Firefox, Chrome, Putty, Blender,…); several DosBox programs and a few emulators; Uplay, Epic, Steam, Origin, GOG, Rockstar launchers; numerous symbolic links/junctions; and, apart from a recent series of CTDs where I’d accidentally deleted my pagefile (I was moving it from one partition to another - did I mention I have >9 partitions across 6 drives?!), I’ve not experienced any real issues with MSFS 2020 even when running multiple applications - hell, I’ve even been defragging, ripping CDs, updating Steam games, and such, whilst running MSFS (and alt-tabbing between them whilst doing so). And I’m ‘only’ running an i5-9600K and a RTX2060S with 16GB of RAM

What I didn’t mention there were the G27 pedals (using UJR), Rift CV1, ye olde MS stick and occasional FaceTrackNoIR use. My ‘rig’ is far from clean and really ought to be the first to crash.
Oh, and a mere 750W PSU that is actually far above my requirements (I actually used to run two GTX 560Tis with it). And a system controlled pagefile sat on the dedicated MSFS2020 SSD partition (not the boot partition).