Waste of time

Have you seen this thread?

[FIXED] CTD Exception code 0xc0000005 Crash to Desktop - Archives / Bugs & Issues - Microsoft Flight Simulator Forums

In summary, and I have experienced this too recently, live traffic appears to play a part in the issue. I know it shouldn’t and hopefully Asobo will find a fix, but it might help you to at least complete your flights.

If this isn’t your problem, it was still worth a try, and I’ll wish you luck in finding a solution.